Coumarins and derivatives
Selleck Chemical LLC Dicoumarol-50mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.
Apexbio Technology LLC Coumarin-3-carboxylic Acid 531-81-7 100mg
Coumarin-3-carboxylic Acid is a coumarin-derived small molecule commonly applied as an investigative tool in biomedical research focusing on signal pathway regulation It is utilized to modulate enzymatic activities and cellular signaling pathways Coumarin-3-carboxylic Acid s biological activity has been studied in the context of its lanthanide complexes for inhibitory effects on cell growth in K-562 cell lines In cell-based studies it demonstrates antiproliferative activity in K-562 cells Based on these pharmacological properties Coumarin-3-carboxylic Acid holds research potential in elucidating biological mechanisms underlying hematologic malignancies and related diseases
Apexbio Technology LLC 3-Nitrocoumarin 28448-04-6 10mg
3-Nitrocoumarin (CAS 28448-04-6) is a selective inhibitor of phospholipase C- (PLC- ) an enzyme involved in cellular signal transduction through the hydrolysis of membrane phospholipids and subsequent generation of secondary messengers By suppressing PLC- catalytic activity 3-Nitrocoumarin disrupts related intracellular signaling pathways thereby enabling investigation of PLC- -mediated mechanisms in various physiological and pathological contexts This compound is widely utilized in studies focused on elucidating the roles of PLC- in disease models and fundamental biomedical research
Apexbio Technology LLC 7-Amino-4-(trifluoromethyl)coumarin 53518-15-3 500mg
7-Amino-4-trifluoromethyl coumarin (CAS 53518-15-3) is a small-molecule antagonist targeting serotonin receptor subtype 1E (HTR1E) galanin receptor 2 (GALR2) and gamma receptor subtype 2 (GalR2) It is designed to antagonize these receptors thereby modulating receptor-mediated signaling pathways 7-Amino-4-trifluoromethyl coumarin exerts its biological activity primarily through receptor antagonism and inhibition of hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4) enzymatic activity In biochemical assays it demonstrates inhibitory activity toward HSD17B4 with reported bioactivity at approximately 21 M Based on these pharmacological properties 7-Amino-4-trifluoromethyl coumarin holds research potential in the investigation of protease activity receptor-mediated signaling and metabolic enzyme regulation
Medchemexpress LLC 3-aminocoumarin (3-aminochromen-2-one) | 1635-31-0 | MFCD00016965 | 99.2% | 161.16 | C9H7NO2 | 250 MG
3-Aminocoumarin (3-aminochromen-2-one) is a coumarin-derived organic intermediate used in research and chemical synthesis. It functions as a building block for the preparation of metal complexes and other functionalized coumarin derivatives, and is supplied as a laboratory research reagent with recommended storage instructions to preserve stability.
- Coumarin-derived intermediate for organic synthesis.
- Suitable for synthesis of metal complexes and functionalized derivatives.
- Molecular formula C9H7NO2; molecular weight 161.16 g/mol.
- Recommended storage: solid at 4°C, protect from light; solutions -80°C (6 months) or -20°C (1 month).
- Provided as a research reagent; follow appropriate safety and handling procedures.
Cayman Chemical CoumarIn BoronIc AcId 50mg
A fluorescent probe for direct detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide; reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s); COH displays ex/em = 332/470 nm, respectively
AARON CHEMICALS LLC 1-Bromo-4-phenylbutane | 13633-25-5 | 213.11 g/mol | 25G
1-Bromo-4-phenylbutane | 13633-25-5 | 213.11 g/mol | 25G
Indofine Chemical 7-Diethylaminocou, 98%, 250 Mg
7-DIETHYLAMINOCOUMARIN 250 MG, Coumarin, C13H15NO2, MW: 217.27, 98%, 20571-42-0, MFCD00232946
Selleck Chemical LLC Esculetin S4711-100mg
Esculetin (Cichorigenin Aesculetin) is a coumarin derivative found in various natural plant products with various biological and pharmaceutical properties including anti-edema anti-inflammatory and anti-tumour effects It inhibits lipoxygenases (LOs)